منابع مشابه
Hypertonic saline for craniotomy?
IN this issue of ANESTHESIOLOGY, Rozet et al. present the findings of a comprehensive study comparing two hyperosmolar agents, hypertonic saline (HS) and mannitol, for brain relaxation during craniotomy. This work calls into question whether sufficient information is now available to advocate substitution of mannitol with HS to promote brain relaxation during routine craniotomy. It was discover...
متن کاملMannitol versus hypertonic saline for brain relaxation in patients undergoing craniotomy.
BACKGROUND Patients with brain tumour usually suffer from increased pressure in the skull due to swelling of brain tissue. A swollen brain renders surgical removal of the brain tumour difficult. To ease surgical tumour removal, measures are taken to reduce brain swelling, often referred to as brain relaxation. Brain relaxation can be achieved with intravenous fluids such as mannitol or hyperton...
متن کاملHypertonic saline and stroke.
Cytotoxic brain edema—swelling of nerve and glial cells—is among the very early pathophysiologic sequelae of focal cerebral ischemia. Once cell swelling has exhausted the cerebral compliance, intracranial pressure increases and, thereby, causes secondary ischemia. Hypertonic solutions, mannitol in particular, have long been used to reduce intracranial pressure. More recently, hypertonic saline ...
متن کاملEffects of hypertonic saline and mannitol on cortical cerebral microcirculation in a rabbit craniotomy model
BACKGROUND Hyperosmolar solutions have been used in neurosurgery to modify brain bulk and prevent neurological deterioration. The aim of this animal study was to compare the short-term effects of equivolemic, equiosmolar solutions of mannitol and hypertonic saline (HTS) on cerebral cortical microcirculation in a rabbit craniotomy model. METHODS Rabbits (weight, 2.0-3.0 kg) were anesthetized, ...
متن کاملNormal Saline vs. Hypertonic Saline Nebulization for Acute Bronchiolitis: A Randomized Clinical Trial
BackgroundWe aimed to compare the efficacy of nebulized hypertonic (3%, 5% and 7%) saline with normal saline in hospitalized infants with acute bronchiolitis.Materials and MethodsIn this triple-blinded randomized clinical trial, 120 children with moderate to severe bronchiolitis randomly assigned into four groups to receive nebulized normal saline (group A), saline 3% (group B), saline 5% (gro...
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2007
ISSN: 0003-3022
DOI: 10.1097/01.anes.0000286923.77106.63